diff --git a/.gitignore b/.gitignore
index 994bbe0..95d72f1 100644
--- a/.gitignore
+++ b/.gitignore
@@ -1,3 +1,4 @@
 bin
 dockcross
 */test/
+Dockerfile
diff --git a/Dockerfile b/Dockerfile
deleted file mode 100644
index 8c8a356..0000000
--- a/Dockerfile
+++ /dev/null
@@ -1,78 +0,0 @@
-FROM debian:jessie
-MAINTAINER Matt McCormick "matt.mccormick@kitware.com"
-
-# Insert this line before "RUN apt-get update" to dynamically
-# replace httpredir.debian.org with a single working domain
-# in attempt to "prevent" the "Error reading from server" error.
-RUN apt-get update && apt-get install -y curl && \
-  sed -i "s/httpredir.debian.org/`curl -s -D - http://httpredir.debian.org/demo/debian/ | awk '/^Link:/ { print $2 }' | sed -e 's@<http://\(.*\)/debian/>;@\1@g'`/" /etc/apt/sources.list
-
-RUN apt-get update && apt-get -y install \
-  automake \
-  autogen \
-  bash \
-  build-essential \
-  bzip2 \
-  ca-certificates \
-  curl \
-  file \
-  git \
-  gzip \
-  libcurl4-openssl-dev \
-  libssl-dev \
-  make \
-  ncurses-dev \
-  pkg-config \
-  libtool \
-  python \
-  rsync \
-  sed \
-  bison \
-  flex \
-  tar \
-  vim \
-  wget \
-  runit \
-  xz-utils && \
-  apt-get -y clean
-
-WORKDIR /usr/share
-RUN git clone https://github.com/nojhan/liquidprompt.git && \
-  cd liquidprompt && \
-  git checkout v_1.11
-COPY imagefiles/.bashrc /root/
-
-# Build and install CMake from source.
-WORKDIR /usr/src
-RUN git clone git://cmake.org/cmake.git CMake && \
-   cd CMake && \
-   git checkout v3.6.1 && \
-   cd .. && mkdir CMake-build && cd CMake-build && \
-   /usr/src/CMake/bootstrap \
-     --parallel=$(nproc) \
-     --prefix=/usr && \
-   make -j$(nproc) && \
-   ./bin/cmake -DCMAKE_USE_SYSTEM_CURL:BOOL=ON \
-     -DCMAKE_BUILD_TYPE:STRING=Release \
-     -DCMAKE_USE_OPENSSL:BOOL=ON . && \
-   make install && \
-   cd .. && \
-   rm -rf CMake*
-# Wrappers that point to CMAKE_TOOLCHAIN_FILE
-
-# Build and install Ninja from source
-RUN git clone https://github.com/martine/ninja.git && \
-   cd ninja && \
-   git checkout v1.7.1 && \
-   python ./configure.py --bootstrap && \
-   ./ninja && \
-   cp ./ninja /usr/bin/ && \
-   cd .. && rm -rf ninja
-COPY imagefiles/cmake.sh /usr/local/bin/cmake
-COPY imagefiles/ccmake.sh /usr/local/bin/ccmake
-
-RUN echo "root:root" | chpasswd
-WORKDIR /work
-ENTRYPOINT ["/dockcross/entrypoint.sh"]
-
-COPY imagefiles/entrypoint.sh imagefiles/dockcross /dockcross/
diff --git a/Dockerfile.in b/Dockerfile.in
new file mode 100644
index 0000000..09d22a4
--- /dev/null
+++ b/Dockerfile.in
@@ -0,0 +1,36 @@
+FROM debian:jessie
+MAINTAINER Matt McCormick "matt.mccormick@kitware.com"
+
+RUN apt-get update && apt-get install -y curl && \
+  sed -i "s/httpredir.debian.org/`curl -s -D - http://httpredir.debian.org/demo/debian/ | awk '/^Link:/ { print $2 }' | sed -e 's@<http://\(.*\)/debian/>;@\1@g'`/" /etc/apt/sources.list
+
+RUN apt-get update && apt-get -y install \
+  automake \
+  autogen \
+  bash \
+  build-essential \
+  bzip2 \
+  ca-certificates \
+  curl \
+  file \
+  git \
+  gzip \
+  libcurl4-openssl-dev \
+  libssl-dev \
+  make \
+  ncurses-dev \
+  pkg-config \
+  libtool \
+  python \
+  rsync \
+  sed \
+  bison \
+  flex \
+  tar \
+  vim \
+  wget \
+  runit \
+  xz-utils && \
+  apt-get -y clean
+
+#include "common.docker"
diff --git a/Makefile b/Makefile
index 99dd453..df74c77 100644
--- a/Makefile
+++ b/Makefile
@@ -71,6 +71,16 @@ linux-ppc64le.test: linux-ppc64le test/run.py
 	$(DOCKER) run --rm dockcross/linux-ppc64le > $(BIN)/dockcross-linux-ppc64le && chmod +x $(BIN)/dockcross-linux-ppc64le
 	$(BIN)/dockcross-linux-ppc64le python test/run.py --languages C
 
+manylinux-x64/Dockerfile: manylinux-x64/Dockerfile.in common.docker
+	sed '/common.docker/ r common.docker' manylinux-x64/Dockerfile.in > manylinux-x64/Dockerfile
+
+manylinux-x64: manylinux-x64/Dockerfile
+	$(DOCKER) build -t $(ORG)/manylinux-x64 -f manylinux-x64/Dockerfile .
+
+manylinux-x64.test: manylinux-x64 test/run.py
+	$(DOCKER) run --rm dockcross/manylinux-x64 > $(BIN)/dockcross-manylinux-x64 && chmod +x $(BIN)/dockcross-manylinux-x64
+	$(BIN)/dockcross-manylinux-x64 /opt/python/cp35-cp35m/bin/python test/run.py
+
 windows-x86: base windows-x86/Dockerfile windows-x86/settings.mk
 	$(DOCKER) build -t $(ORG)/windows-x86 windows-x86
 
@@ -85,6 +95,9 @@ windows-x64.test: windows-x64 test/run.py
 	$(DOCKER) run --rm dockcross/windows-x64 > $(BIN)/dockcross-windows-x64 && chmod +x $(BIN)/dockcross-windows-x64
 	$(BIN)/dockcross-windows-x64 python test/run.py --exe-suffix ".exe"
 
+Dockerfile: Dockerfile.in common.docker
+	sed '/common.docker/ r common.docker' Dockerfile.in > Dockerfile
+
 base: Dockerfile
 	$(DOCKER) build -t $(ORG)/base .
 
diff --git a/README.rst b/README.rst
index 30c85a2..9be40f6 100644
--- a/README.rst
+++ b/README.rst
@@ -99,6 +99,14 @@ dockcross/linux-x86
   |linux-x86-images| Linux i686 cross compiler.
 
 
+.. |manylinux-x64-images| image:: https://badge.imagelayers.io/dockcross/manylinux-x64:latest.svg
+  :target: https://imagelayers.io/?images=dockcross/manylinux-x64:latest
+
+dockcross/manylinux-x64
+  |manylinux-x64-images| Docker `manylinux <https://github.com/pypa/manylinux>`_ image for building Linux x86_64 / amd64 `Python wheel packages <http://pythonwheels.com/>`_.
+  Also has support for the dockcross script, and it has installations of CMake, Ninja, and `scikit-build <http://scikit-build.org>`_
+
+
 .. |windows-x64-images| image:: https://badge.imagelayers.io/dockcross/windows-x64:latest.svg
   :target: https://imagelayers.io/?images=dockcross/windows-x64:latest
 
diff --git a/circle.yml b/circle.yml
index 71f6714..097a1f8 100644
--- a/circle.yml
+++ b/circle.yml
@@ -19,6 +19,7 @@ dependencies:
     - docker pull dockcross/linux-ppc64le
     - docker pull dockcross/linux-x64
     - docker pull dockcross/linux-x86
+    - docker pull dockcross/manylinux-x64
     - docker pull dockcross/windows-x64
     - docker pull dockcross/windows-x86
 
@@ -34,6 +35,7 @@ test:
     - make linux-ppc64le.test
     - make linux-x64.test
     - make linux-x86.test
+    - make manylinux-x64.test
     - make windows-x64.test:
         timeout: 3000
     - make windows-x86.test:
@@ -54,5 +56,6 @@ deployment:
       - docker push dockcross/linux-ppc64le
       - docker push dockcross/linux-x64
       - docker push dockcross/linux-x86
+      - docker push dockcross/manylinux-x64
       - docker push dockcross/windows-x64
       - docker push dockcross/windows-x86
diff --git a/common.docker b/common.docker
new file mode 100644
index 0000000..031e6d2
--- /dev/null
+++ b/common.docker
@@ -0,0 +1,37 @@
+WORKDIR /usr/share
+RUN git clone "https://github.com/nojhan/liquidprompt.git" && \
+  cd liquidprompt && \
+  git checkout v_1.11
+COPY imagefiles/.bashrc /root/
+
+WORKDIR /usr/src
+RUN git clone "git://cmake.org/cmake.git" CMake && \
+   cd CMake && \
+   git checkout v3.6.1 && \
+   cd .. && mkdir CMake-build && cd CMake-build && \
+   /usr/src/CMake/bootstrap \
+     --parallel=$(nproc) \
+     --prefix=/usr && \
+   make -j$(nproc) && \
+   ./bin/cmake \
+     -DCMAKE_BUILD_TYPE:STRING=Release \
+     -DCMAKE_USE_OPENSSL:BOOL=ON . && \
+   make install && \
+   cd .. && \
+   rm -rf CMake*
+
+RUN git clone "https://github.com/martine/ninja.git" && \
+   cd ninja && \
+   git checkout v1.7.1 && \
+   ([ -e /opt/python/cp35-cp35m/bin/python ] && /opt/python/cp35-cp35m/bin/python ./configure.py --bootstrap) || python ./configure.py --bootstrap && \
+   ./ninja && \
+   cp ./ninja /usr/bin/ && \
+   cd .. && rm -rf ninja
+COPY imagefiles/cmake.sh /usr/local/bin/cmake
+COPY imagefiles/ccmake.sh /usr/local/bin/ccmake
+
+RUN echo "root:root" | chpasswd
+WORKDIR /work
+ENTRYPOINT ["/dockcross/entrypoint.sh"]
+
+COPY imagefiles/entrypoint.sh imagefiles/dockcross /dockcross/
diff --git a/manylinux-x64/Dockerfile.in b/manylinux-x64/Dockerfile.in
new file mode 100644
index 0000000..b7254fa
--- /dev/null
+++ b/manylinux-x64/Dockerfile.in
@@ -0,0 +1,28 @@
+FROM quay.io/pypa/manylinux1_x86_64:latest
+MAINTAINER Matt McCormick "matt.mccormick@kitware.com"
+
+#include "common.docker"
+
+RUN cd /opt && \
+  wget "http://smarden.org/runit/runit-2.1.2.tar.gz" && \
+  tar xvzf runit-2.1.2.tar.gz && \
+  cd admin/runit-2.1.2 && \
+  ./package/install
+
+COPY manylinux-x64/install-skbuild.sh /usr/local/bin
+RUN /usr/local/bin/install-skbuild.sh
+
+ENV CROSS_TRIPLE x86_64-linux-gnu
+ENV CROSS_ROOT /opt/rh/devtoolset-2/root/usr/bin
+ENV AS=${CROSS_ROOT}/as \
+    AR=${CROSS_ROOT}/ar \
+    CC=${CROSS_ROOT}/gcc \
+    CPP=${CROSS_ROOT}/cpp \
+    CXX=${CROSS_ROOT}/g++ \
+    LD=${CROSS_ROOT}/ld
+
+COPY linux-x64/${CROSS_TRIPLE}-noop.sh /usr/bin/${CROSS_TRIPLE}-noop
+
+COPY manylinux-x64/Toolchain.cmake ${CROSS_ROOT}/../lib/
+ENV CMAKE_TOOLCHAIN_FILE ${CROSS_ROOT}/../lib/Toolchain.cmake
+ENV DEFAULT_DOCKCROSS_IMAGE dockcross/manylinux-x64
diff --git a/manylinux-x64/Toolchain.cmake b/manylinux-x64/Toolchain.cmake
new file mode 100644
index 0000000..ef7cd91
--- /dev/null
+++ b/manylinux-x64/Toolchain.cmake
@@ -0,0 +1,12 @@
+set(CMAKE_SYSTEM_NAME Linux)
+set(CMAKE_SYSTEM_VERSION 1)
+set(CMAKE_SYSTEM_PROCESSOR x86_64)
+
+set(cross_triple "x86_64-linux-gnu")
+
+set(CMAKE_C_COMPILER /opt/rh/devtoolset-2/root/usr/bin/gcc)
+set(CMAKE_CXX_COMPILER /opt/rh/devtoolset-2/root/usr/bin/g++)
+set(CMAKE_ASM_COMPILER /opt/rh/devtoolset-2/root/usr/bin/as)
+set(CMAKE_Fortran_COMPILER /opt/rh/devtoolset-2/root/usr/bin/gfortran)
+
+set(CMAKE_CROSSCOMPILING_EMULATOR /usr/bin/${cross_triple}-noop)
diff --git a/manylinux-x64/install-skbuild.sh b/manylinux-x64/install-skbuild.sh
new file mode 100755
index 0000000..a028024
--- /dev/null
+++ b/manylinux-x64/install-skbuild.sh
@@ -0,0 +1,5 @@
+#!/bin/bash
+
+for PIP in /opt/python/*/bin/pip; do
+  $PIP install scikit-build==0.3.0
+done